screenCORE   screenCORE are 1 µm sized fluorescent, non-magnetic, monodisperse microspheres based on a silica matrix. The advantage of silica microspheres compared to polystyrene microspheres are the inert and stable solid-phase silica matrix without autofluorescence and are autoclaved for sterile applications. Furthermore through the higher mechanical and chemical stability, hydrophilic character, resistance to microbiological degradation and compatible with organic solvents is it useful for biochromatiography applications.   FluorescenceType FluorescenceColor Excitation Emission screenCORE/B blue 400 nm 420 nm screenCORE/GQ green 423 nm 503 nm screenCORE/GF green 436 nm 520 nm screenCORE/GA green 460 nm 550 nm screenCORE/G green 502 nm 525 nm screenCORE/OE orange 510 nm 595 nm screenCORE/O orange 526 nm 555 nm screenCORE/OP orange 536 nm 617 nm screenCORE/RR red 540 nm 625 nm screenCORE/R red 633 nm 672 nm             screenCORE - active   Application: Activated particles for custom-made covalent binding of biological substances Formulation: suspension in ddH2O, autoclaved Concentration: 50 mg/ml Particle size: 1.0 µm See: Coupling-Protocols     Functional Group Product Number Quantity (ml) Activation / Coupling Product Information Reference Number screenCORE-Amine -O-(CH2)3-NH2 6101-16101-5 15 Carbodiimide method Mannich reaction see coupling protocol: C2/3 - screenCORE-Carboxyl -O-(CH2)3-COOH 6102-16102-5 15 Carbodiimide method see coupling protocol: C1 - screenCORE-Hydrazide -O-(CH2)3~CO-NH-NH2 6104-16104-5 15 Oxidized carbohydrates see coupling protocol: C5 - screenCORE-Hydroxyl -Si-(CH2)3-OH 6105-16105-5 15 Cyanogen bromide activation see coupling protocol: A7 - screenCORE-PGL -Si-(CH2)3 6106-16106-5 15 For covalent coupling of bioligands see protocol: A4 - screenCORE-Thiol -Si-(CH2)3-SH 6108-16108-5 15 Maleimides see coupling protocol: A6 - screenCORE-Silanol -Si-OH 6107-16107-5 15 Binding of DNA/RNA, adsorption of biomolecules -   screenCORE - affinity   Application: Affinity chromatography Formulation: buffer suspension, 0.01 NaN3 Concentration: 10 mg/ml Particle sizes: 1.0 µm See: Coupling-Protocols   Affinity Group Product Number Quantity (ml) For Purification Product Information Reference Number screenCORE-Biotin 6201-16201-5 15 Avidin / streptavidin labeled molecules - screenCORE-Boronic acid 6207-16207-5 15 Ribonucleotides, sugars via cis-diols see protocol: CB14 - screenCORE-Concanavalin A 6208-16208-5 15 Bacteria, glycoproteins - screenCORE-Goat anti-rabbit IgG(whole molecule) 6206-16206-5 15 For binding of secondary antibody See protocol: CB11 - screenCORE-Goat anti-mouse IgG(whole molecule) 6202-16202-5 15 For binding of secondary antibody See protocol: CB4 - screenCORE-Protein A 6203-16203-5 15 Antibodies See protocol: CB2 - screenCORE-Protein G 6204-16204-5 15 - screenCORE-Streptavidin 6205-16205-5 15 Biotin-labeled molecules See protocol: CB1 -