nano-screenMAG Confocal microscopy imaging of nano-screenMAG/B-ARA nanoparticles after uptake in prostate cancer cells (Du-145). (Data kindly provided by Badr Haitham and Dr. Joerg Hoheisel DKFZ-Heidelberg, Germany) nano-screenMAG - is an aqueous dispersion of magnetic-fluorescent nanoparticles available in hydrodynamic diameters of 100 nm, 150 and 200 nm. nano-screenMAG particles consist of a magnetite core which is first covered by a lipophilic fluorescence dye. A second layer envelops the particle with a hydrophilic polymer which protects the particles against aggregation by foreign ions. Terminal functional groups such as ion-exchange groups or reactive groups for covalent immobilization can be used for binding to biomolecules.       nano-screenMAGFluorescenceType Fluorescence Color Excitation Emission nano-screenMAG/B blue 378 nm 413 nm nano-screenMAG/G green 476 nm 490 nm nano-screenMAG/O orange 524 nm 539 nm nano-screenMAG/P pink 547 nm 581 nm nano-screenMAG/R red 578 nm 613 nm   NOTE: The fluorescence of the nano-screenMAG particles is only detectable on the same side where the excitation takes place. Please note that there is a difference in fluorescence observation between dissolved fluorescence molecules and solid fluorescence particles. Fluorescence spectrophotometer with a fluorescence detection unit with an angle of 90° to the excitation source will detect no or only weak fluorescence signals.      Application: Magnetic separation, labeling and fluorescence detection Concentration: 25 mg/ml Particle sizes: 100 nm, 150 nm, 200 nm; For ordering mention the fluorescence color         Product Polymer Matrix Product Number Quantity (ml) Application Product Information Reference Number nano-screenMAG-ARA Glucuronic acid 4415-14415-5 15 Weak cation exchanger; for covalent coupling of biomolecules (antibodies or proteins) See protocol: A10 6.06, 6.13, 10.49 nano-screenMAG-Chitosan Chitosan 4418-14418-5 15 linear and biogradable polymer with amino-groups. 6.03, 6.17, 10.47 nano-screenMAG-CMX Carboxymethyl-dextran 4406-14406-5 15 Weak cation-exchanger for covalent coupling of biomolecules (antibodies or proteins) See protocol: A11 6.03, 6.12 nano-screenMAG-D Starch 4401-14401-5 15 Isolation of lysosomes, MRI-diagnostic, for covalent coupling of biomolecules (antibodies or proteins) See protocol: A9 6.02, 6.11, 6.16,6.18, 10.44, 10.46 nano-screenMAG-DEAE DEAE-starch 4402-14402-5 15 Binds negative groups of cells, bacteria, viruses 4.15, 6.19 nano-screenMAG-DP Phosphate-starch 4403-14403-5 15 Purification of basic proteins, drug targeting - nano-screenMAG-DXS Dextran-sulfate 4405-14405-5 15 Strong cation exchanger - nano-screenMAG-Lipid Lipid 4419-14419-5 15 Negatively charged phosphatidylcholine 4.15, 6.03, 6.16 nano-screenMAG-PAA Polyaspartic acid 4408-14408-5 15 Strong cation exchanger - nano-screenMAG-PAD Polyacrylamide 4409-14409-5 15 Surface modification - nano-screenMAG-PAS Polyacrylic acid 4410-14410-5 15 Weak cation-exchanger 6.15 nano-screenMAG-PEA Polydimethylamine 4417-14417-5 15 Terminal amino groups for conjugation of biomolecules - nano-screenMAG-PEG/P Polyethylene glycol α-, ω-diphosphate 4416-14416-5 15 Aqueous dispersion of polyethylene glycol α-, ω-diphosphate covered magnetic nanoparticles - nano-screenMAG-PMO Poly(maleic acid-co-olefin) 4421-14421-5 15 For hydrophilic / hydrophobe interaction 4.15 nano-screenMAG-PS Polystyrenesulfonate 4411-14411-5 15 Strong cation-exchanger - nano-screenMAG-UC/A Magnetite uncoated 4414-14414-5 15 Adsorption of biomolecules stabilized by cross-linking; anionic charged - nano-screenMAG-UC/C Magnetite uncoated 4430-14430-5 15 Adsorption of biomolecules stabilized by cross-linking; cationic charged -   nano-screenMAG-affinity   nano-screenMAG-affinity - bioaffine ligands are covalently bound to the magnetic-fluorescent particles. High selectivity and high capacity make these products an ideal tool for the isolation or detection of specific biomolecules.   Application: Affinity chromatography and fluorescence detection Concentration: 10 mg/ml Particle sizes: 100 nm, 150 nm, 200 nm; For ordering mention the fluorescence color       nano-screenMAG with Ligand Product Number Quantity (ml) Application for: Purification / Binding Product Information Reference Number nano-screenMAG-Biotin 4501-14501-5 15 Avidin / streptavidin labeled molecules - nano-screenMAG-Goat anti-mouse IgG (whole molecule) 4502-14502-5 15 Secondary antibody See protocol: B5 - nano-screenMAG-Protein A 4503-14503-5 15 Antibodies See protocol: B4 - nano-screenMAG-Protein G 4504-14504-5 15   - nano-screenMAG-Streptavidin 4505-14505-5 15 Biotin-labeled molecules See protocol: B1 8.06 nano-screenMAG-Casein 4506-14506-5 15 RNA polymerase - nano-screenMAG-Gelatin 4507-14507-5 15 Fibronectin - nano-screenMAG-Heparin 4508-14508-5 15 Lipoprotein, lipase, RNA-polymerase -