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제품 담당: 김하경 매니저
hkkim@jcbio.co.kr
Tel. 02-568-7320

제품소개

New PEGylation reagents chemicell offers new polyethylene glycol (PEG) derivates which are synthesized under pharmaceutical conditions in water without any organic solvents and without toxic agents. All PEG derivates are delivered as sterile aqueous solutions. Application The protection of biological macromolecules, peptides, antibodies, proteins, and oligonucleotides is of extreme importance in biological, immunological and pharmacological applications. There is growing interest of PEG and its α- and/or ω-substituted derivates and the protection offered by the covalent attachment of PEG to target molecules. PEGylation has become the method of choice for the delivery of bio-pharmaceuticals. Linear PEGs can offer one or two reactive groups that can bind with a functional group on the target molecule. Advantages of PEGylation Increased bioavailability Increased blood circulation of the target biomolecule / drug Shielding receptor-mediated uptake by the reticuloendothelial system (RES) Shielding of antigenic and immunogenic epitopes Preventing recognition and degradation by proteolytic enzymes Increasing the apparent size of polypeptides, thus reducing the renal filtration and altering biodistribution Optimized pharmacokinetics Decreased immunogenicity Description Structure Formula   Product Number      PEG MW      (Da)       Amount       Product Information Polyethylene glycol di-succinic acid α,ω-Di-succinic acid poly-ethylene glycol PDS6-1PDS6-5 6000 1 g5 g PDS8-1PDS8-5 8000 1 g5 g PDS20-1PDS20-5 20000 1 g5 g Polyethylene glycol succinic acid α-Methoxy-ω-succinic acid polyethylene glycol PMS5-1PMS5-5 5000 1 g5 g Polyethylene glycol di-phosphate α,ω-Di-phosphate polyethylene glycol PDP6-1PDP6-5 6000 1 g5 g PDP8-1PDP8-5 8000 1 g5 g PDP20-1PDP20-5 20000 1 g5 g Polyethylene glycol phosphate α-Methoxy-ω-phosphate poly-ethylene glycol PMP5-1PMP5-5 5000 1 g5 g Polyethylene glycol di-Cibacron Blue α,ω-di-Cibacron Blue polyethylene glycol PDC6-1PDC6-5 6000 1 g5 g PDC8-1PDC8-5 8000 1 g5 g PDC20-1PDC20-5 20000 1 g5 g Polyethylene glycol Cibacron Blue α-Methoxy-ω-Cibacron Blue polyethylene glycol PDC5-1PDC5-5 5000 1 g5 g Polyethylene glycol di-fluorescein α,ω-Di-fluorescein poly-ethylene glycol PDF6-1PDF6-5 6000 100 mg500 mg PDF8-1PDF8-5 8000 100 mg500 mg PDF20-1PDF20-5 20000 100 mg500 mg Polyethylene glycol fluorescein α-Methoxy-ω-fluorescein polyethylene glycol PMF5-1PMF5-5 5000 100 mg500 mg Polyethylene glycol di-amine α,ω-Di-amine polyethylene glycol PDA6-1PDA6-5 6000 1 g5 g PDA8-1PDA8-5 8000 1 g5 g PDA20-1PDA20-5 20000 1 g5 g Polyethylene glycol amine α-Methoxy-ω-amine polyethylene glycol PMA5-1PMA5-5 5000 1 g5 g Polyethylene glycol di-Rhodamine α,ω-Di-Rhodamine polyethylene glycol PDR6-1PDR6-5 6000 100 mg500 mg PDR8-1PDR8-5 8000 100 mg500 mg PDR20-1PDR20-5 20000 100 mg500 mg Polyethylene glycol Rhodamine α-Methoxy-ω-Rhodamine polyethylene glycol PMR5-1PMR5-5 5000 100 mg500 mg  

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